3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazapine → 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine

Participants

Reaction Steps

By a procedure similar to that described in Example 35, 0.245 g of 3-methylsulfinyl-11H-s-triazolo [3,4-b][3]benzazepine, in lieu of 3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazepine, was reacted with 1.2 ml of 1 N-sodium ethoxide/ethanol in 2 ml of ethanol to obtain 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine as crystals. Recrystallization from acetone yielded colorless needles, melting point 143°-144° C. The infrared absorption spectrum of this product was identical with that of the compound obtained in Example 35.

Provenance & Evidence