HCID 19082314, compound → HCID 19034209, compound

HRID 265308Notes

Reaction equation

HRID 265308 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][O:9][CH2:10][CH2:11][S:12][CH2:13][CH2:14][CH:15]1OCC[O:16]1>C(O)=O>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][O:9][CH2:10][CH2:11][S:12][CH2:13][CH2:14][CH:15]=[O:16]

Participants

3

Reactant 1

HCID 19082314HCID 19082314, compound

Product 1

HCID 19034209HCID 19034209, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

The material from step b) (0.850 g) was dissolved in 80% formic acid (10 ml) and left to stand at room temperature for 22 hours. The mixture was partitioned between ether and water. The layers were separated and the aqueous layer extracted with ether. The ethereal extracts were combined, washed with brine, dried (MgSO4) and evaporated under reduced pressure to yield the subtitled compound as an oil (0.70 g).

Workup

  1. waitleft
  2. customThe mixture was partitioned between ether and water
  3. customThe layers were separated
  4. extractionthe aqueous layer extracted with ether
  5. washwashed with brine
  6. dry with materialdried (MgSO4)
  7. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-ef9c1b1738924119b837860bceb0414f
Source dataset
uspto-grants-1997_07
Patent number
US05648370

Reaction notes

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