Sodium Methoxide → 3-methoxy-11-phenyl-11H-s-triazolo[3,4-b][3]benzazepine

HRID 26531Notes

Reaction equation

HRID 26531 reaction equation
CS([C:5]1[N:14]2[C:8]([CH:9]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:10]3[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=3[CH:12]=[CH:13]2)=[N:7][N:6]=1)(=O)=O.[CH3:25][O-:26].[Na+]>>[CH3:25][O:26][C:5]1[N:14]2[C:8]([CH:9]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:10]3[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=3[CH:12]=[CH:13]2)=[N:7][N:6]=1

Participants

3

Reactant 2

HCID 10942334Sodium MethoxideHCID 213233363-methylsulfonyl-11-phenyl-11H-s-triazolo[3,4-b][3]benzazepine

Product 1

HCID 213233983-methoxy-11-phenyl-11H-s-triazolo[3,4-b][3]benzazepine

Procedure

The reaction of 3-methylsulfonyl-11-phenyl-11H-s-triazolo[3,4-b][3]benzazepine with sodium methoxide yielded 3-methoxy-11-phenyl-11H-s-triazolo[3,4-b][3]benzazepine. Colorless prisms (as recrystallized from aqueous methanol), melting point: 183°-184° C.

Sources & evidence

ORD record
ord-ee7069382bb34b7aa90aeb4921fb8a59
Source dataset
uspto-grants-1979_04
Patent number
US04150139

Reaction notes

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