Bromine → 2-Bromo-5-hydroxyindan-1,3-dione

HRID 265344Notes

Reaction equation

HRID 265344 reaction equation
[Br:1]Br.[OH:3][C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[C:9](=[O:13])[CH2:8][C:7]2=[O:14]>C(Cl)(Cl)Cl>[Br:1][CH:8]1[C:7](=[O:14])[C:6]2[C:10](=[CH:11][CH:12]=[C:4]([OH:3])[CH:5]=2)[C:9]1=[O:13]

Participants

4

Reactant 2

HCID 24408BromineHCID 190343335-hydroxy-2,3-dihydro-1H-indene-1,3-dione

Product 1

HCID 190342852-Bromo-5-hydroxyindan-1,3-dione

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Conditions

Temperature
50 °C

Procedure

0.02 mol bromine was added dropwise to a solution of 0.02 mol of 5-hydroxyindan-1,3-dione in 60 ml chloroform. The reaction mixture was agitated at 50° C. for 30 minutes and the precipitate obtained after evaporation of the solvent was recrystallised.

Workup

  1. customthe precipitate obtained
  2. customafter evaporation of the solvent
  3. customwas recrystallised

Sources & evidence

ORD record
ord-ec428e74b4b74bc394aeb405307d4ac3
Source dataset
uspto-grants-1997_07
Patent number
US05648381

Reaction notes

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