HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Ethyl Ketone → 1,4,5-Triphenyl-2-(7-bromoheptyloxy)imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Ethyl Ketone | HCID 6569 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,4,5-Triphenyl-1,3-dihydro-2H-imidazol-2-one | HCID 628544 | — |
| Reactant | 4,4-Dibromoheptane | HCID 21679102 | — |
| Product | 1,4,5-Triphenyl-2-(7-bromoheptyloxy)imidazole | HCID 22916412 | 21% |
Reaction Steps
A mixture of 1,4,5-triphenylimidazol-2-one (15.3 g), dibromoheptane (50.6 g) and potassium carbonate (13.8 g) was heated at reflux temperature in dry butanone (750 ml) for 20 hours. The mixture was cooled, filtered and the filtrate evaporated to an oil which was chromatographed on silica gel (hexane/ethyl acetate) to give 1,4,5-triphenyl-2-(7-bromoheptyloxy)imidazole (5.0 g, 21%) as a white solid, m.p. 97°-9° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05648373 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-0cef1b1cd8b2483ca68397192a695509 |
| Source note | uspto-grants-1997_07 |