Sodium Hydroxide → HCID 22916420, compound

HRID 265404Notes

Reaction equation

HRID 265404 reaction equation
C[O:2][C:3]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]1[N:16]=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:14]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[N:13]1)=[O:4].[OH-].[Na+]>>[C:3]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]1[N:16]=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:14]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[N:13]1)([OH:4])=[O:2]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 22916397HCID 22916397, compound

Product 1

HCID 22916420HCID 22916420, compoundYield 79%

Procedure

2-(7-Methoxycarbonylheptyl)-4,5-diphenyltriazole (1 g) was reacted with 2N sodium hydroxide in a method similar to Example 58. Recrystallisation from ethanol and water gave 2-(7-carboxyheptyl)-4,5-diphenyltriazole (0.76 g, 79%) as a white solid, m.p. 86°-88° C.

Workup

  1. customRecrystallisation from ethanol and water

Sources & evidence

ORD record
ord-359fbd04aa7247099e6571b1e1c88996
Source dataset
uspto-grants-1997_07
Patent number
US05648373

Reaction notes

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