Ammonia → HCID 13673275, compound

HRID 265422Notes

Reaction equation

C1([N:7]2[C:11]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[C:10]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[N:9]=[C:8]2[O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][C:32](O)=[O:33])C=CC=CC=1.S(Cl)(Cl)=O.[NH3:39]>>[C:12]1([N:7]2[C:11]([C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=3)=[C:10]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[N:9]=[C:8]2[O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][C:32]([NH2:39])=[O:33])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 3

HCID 222Ammonia

HCID 24386Thionyl Chloride

HCID 65676Octimibate

Product 1

HCID 13673275HCID 13673275, compound

Procedure

8-(1,4,5-Triphenylimidazol-2-yloxy)octanoic acid was treated with thionyl chloride followed by ammonia to give the title compound, m.p. 152.5°-153.5° C., Found: C, 76.6; H, 7.0; N, 9.1%: C29H31N3O2 requires: C, 76.8; H, 6:9; N, 9.3%

Sources & evidence

ORD record: ord-1fe2375d34474ca4a496ee572ca1cdcf
Source dataset: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05648373

Reaction notes

Loading…