Acetic Acid → Tetrafluorophthalic anhydride

HRID 265659Notes

Reaction equation

HRID 265659 reaction equation
F[C:2]1(F)[C:10]2[C:5](=[C:6]([F:14])[C:7]([F:13])=[C:8]([F:12])[C:9]=2[F:11])[C:4](=[O:15])[O:3]1.C(O)(=[O:19])C>>[F:11][C:9]1[C:8]([F:12])=[C:7]([F:13])[C:6]([F:14])=[C:5]2[C:4](=[O:15])[O:3][C:2](=[O:19])[C:10]=12

Participants

3

Reactant 2

HCID 176Acetic AcidHCID 11032047Perfluoro-phthalide

Product 1

HCID 69545Tetrafluorophthalic anhydrideYield 87.5%

Procedure

Into a 300 ml glass reactor equipped with a reflux condenser and a stirrer, 100 g (0.413 mol) of the 3,3,4,5,6,7-hexafluoro-1-[3H]-isobenzofuranone obtained in Example 2, and 100 ml of acetic acid were charged, and the mixture was reacted for 48 hours under reflux. Then, the reaction mixture was separated by distillation to obtain 79.5 g of tetrafluorophthalic anhydride. The yield was 87.5%.

Workup

  1. customInto a 300 ml glass reactor equipped with a reflux condenser and a stirrer
  2. customthe mixture was reacted for 48 hours
  3. temperatureunder reflux
  4. customThen, the reaction mixture was separated by distillation

Sources & evidence

ORD record
ord-d04631d920af44e98aa80b7bec9f8d63
Source dataset
uspto-grants-1997_07
Patent number
US05648504

Reaction notes

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