4-(Difluoromethoxy)phenol → HCID 178444229, compound

HRID 265989Notes

Reaction equation

HRID 265989 reaction equation
[F:1][CH:2]([F:11])[O:3][C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1.[CH2:12]([Si:19]1(C2C=CC=CC=2)[CH2:24][CH2:23][CH:22]([C:25](O)=[O:26])[CH2:21][CH2:20]1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>>[CH2:12]([Si@H:19]1[CH2:20][CH2:21][C@H:22]([C:25]([O:10][C:7]2[CH:6]=[CH:5][C:4]([O:3][CH:2]([F:11])[F:1])=[CH:9][CH:8]=2)=[O:26])[CH2:23][CH2:24]1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

3

Reactant 2

HCID 27741244-(Difluoromethoxy)phenolHCID 190321564-n-Heptyl-4-phenyl-4-silacyclohexanecarboxylic acid

Product 1

HCID 178444229HCID 178444229, compound

Procedure

The general procedure of Example 3 was repeated using 4-difluoromethoxyphenol and 4-n-heptyl-4-phenyl-4-silacyclohexanecarboxylic acid, thereby obtaining the intended product.

Workup

  1. customobtaining the intended product

Sources & evidence

ORD record
ord-129f049ecc164411b54d2b54572dbe8f
Source dataset
uspto-grants-1997_07
Patent number
US05650092

Reaction notes

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