1-(2-Hydroxyethyl)piperazine → HCID 67715069, compound

HRID 266033Notes

Reaction equation

Cl[C:2]1[CH:15]=[C:14]([CH3:16])[C:13]2[C:12](=[O:17])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5](=[O:18])[C:4]=2[C:3]=1[CH3:19].[OH:20][CH2:21][CH2:22][N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>O>[OH:20][CH2:21][CH2:22][N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH:24]1[C:3]1([CH3:19])[C:4]2[C:5](=[O:18])[C:6]3[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=3)[C:12](=[O:17])[C:13]=2[C:14]([CH3:16])=[CH:15][CH2:2]1

Participants

Conditions

Temperature: 150 °C

Procedure

A mixture of 2-chloro-1,4-dimethylanthraquinone (1 g) and 1-(2-hydroxyethyl)piperazine (5 g) is heated at 150° C. for 30 min. After cooling to room temperature, water is added, and the material is filtered. Recrystallization from chloroform yields 1-[1-(2-hydroxyethyl)piperazinyl]-1,4-dimethylanthraquinone.

Workup

temperatureAfter cooling to room temperature
filtrationthe material is filtered
customRecrystallization from chloroform

Sources & evidence

ORD record: ord-341fd349f5884b4eb5a120011e036384
Source dataset: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05650399

Reaction notes

Loading…