Potassium Hydroxide → HCID 178441894, compound

HRID 266056Notes

Reaction equation

HRID 266056 reaction equation
[CH2:1]([C:5]1[C:17]([CH2:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=3[C:31]3[NH:35][N:34]=[N:33][N:32]=3)=[CH:21][CH:20]=2)=[C:8]2[C:9]([C:13]([O:15]C)=[O:14])=[CH:10][CH:11]=[CH:12][N:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4].[OH-].[K+]>C(O)(C)(C)C>[CH2:1]([C:5]1[C:17]([CH2:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=3[C:31]3[NH:32][N:33]=[N:34][N:35]=3)=[CH:21][CH:20]=2)=[C:8]2[C:9]([C:13]([OH:15])=[O:14])=[CH:10][CH:11]=[CH:12][N:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 178441895HCID 178441895, compound

Product 1

HCID 178441894HCID 178441894, compound

Reagents, catalysts & solvents 1

HCID 6386tert-ButanolSolvent

Procedure

Using the procedure of Example 15, 1.02 g of the product of Example 20, 50 ml. of terbutyl alcohol and 25 ml of potassium hydroxide were reacted to obtain after recrystallization from acetonitrile, 686 mg of the expected product melting at 214° C.

Workup

  1. customto obtain
  2. customafter recrystallization from acetonitrile, 686 mg of the expected product melting at 214° C.

Sources & evidence

ORD record
ord-1193c23fe89349428f3edf643540e71c
Source dataset
uspto-grants-1997_07
Patent number
US05650414

Reaction notes

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