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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 266139Generated: October 26, 2026

1-Propanamine, N-ethyl- → ethyl 2-(N-ethyl-N-propylaminomethyl)-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylate

https://huagongshe.com/reaction/266139

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Propanamine, N-ethyl-HCID 88398—
ReactantEthyl 2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylateHCID 21851143—
Productethyl 2-(N-ethyl-N-propylaminomethyl)-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylateHCID 22097653—

Reaction Steps

According to the same manner as that described in Example 29, ethyl 2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylate was reacted with N-ethyl-N-propylamine to give ethyl 2-(N-ethyl-N-propylaminomethyl)-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylate. Colorless prisms, mp. 105°-106° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05650410
Source datasetuspto-grants-1997_07
ORD IDord-4d9ae814e9c949e6b08d33ec0e04f856
Source noteuspto-grants-1997_07