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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 266144Generated: October 26, 2026

Diethylamine → ethyl 6-chloro-2-(N,N-diethylaminomethyl)-4-phenylquinoline-3-carboxylate

https://huagongshe.com/reaction/266144

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylamineHCID 8021—
ReactantEthyl 6-chloro-2-(chloromethyl)-4-phenyl-3-quinolinecarboxylateHCID 14417743—
Productethyl 6-chloro-2-(N,N-diethylaminomethyl)-4-phenylquinoline-3-carboxylateHCID 14417747—

Reaction Steps

According to the same manner as that described in Example 33, ethyl 6-chloro-2-chloromethyl-4-phenylquinoline-3-carboxylate was reacted with diethylamine to give ethyl 6-chloro-2-(N,N-diethylaminomethyl)-4-phenylquinoline-3-carboxylate. This compound was recrystallized from ethanol. Colorless prisms, mp. 107°-108° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05650410
Source datasetuspto-grants-1997_07
ORD IDord-741a65828ec247d49dff949b12c03b5b
Source noteuspto-grants-1997_07