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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 266157Generated: October 30, 2026

Sec-Butylamine → HCID 19032344, compound

https://huagongshe.com/reaction/266157

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSec-ButylamineHCID 24874—
Reactant2-Chloromethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinazolineHCID 10785656—
ProductHCID 19032344HCID 19032344—

Reaction Steps

According to the same manner as that described in Example 56, 2-chloromethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinazoline was reacted with sec-butylamine to give 2-(sec-butylaminomethyl)-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinazoline. This compound was recrystallized from ethyl acetate - hexane. Colorless prisms, mp. 118°-120° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05650410
Source datasetuspto-grants-1997_07
ORD IDord-67ecece0cd1e4412a168306752f69818
Source noteuspto-grants-1997_07