HuagongsheHuagongshe Chemistry Print Report · For research reference only
16-Hydroxyhexadecanoic acid → 2-Dimethylaminopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 16-Hydroxyhexadecanoic acid | HCID 10466 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | CID 11268547 | HCID 11268547 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Dimethylaminopyridine | HCID 21885 | — |
Reaction Steps
Following a procedure similar to that described in Example 12, but using 365 mg of radicicol, 681 mg of 16-hydroxyhexadecanoic acid, 20 ml of dry tetrahydrofuran, 516 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 661 mg of the title compound were obtained as crystals melting at 85°-86° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05650430 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-1a28e979c7d848798395f7881fc15359 |
| Source note | uspto-grants-1997_07 |