Dichloromethane → 2-Dimethylaminopyridine

HRID 266194Notes

Reaction equation

HRID 266194 reaction equation
C[C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.[C:26]([CH2:29][CH2:30][CH2:31][CH2:32]CCCCCCC(Cl)=O)(=O)[NH2:27].[C:42](CCCCCCCCCCC(O)=O)(=O)[NH2:43].[CH2:58](Cl)Cl>N1C=CC=CC=1>[CH3:58][N:43]([C:26]1[CH:29]=[CH:30][CH:31]=[CH:32][N:27]=1)[CH3:42]

Participants

6

Reactant 4

HCID 6344DichloromethaneHCID 10889696HCID 10889696, compoundHCID 11268547CID 11268547HCID 19032996HCID 19032996, compound

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Following a procedure similar to that described in Example 1, but using 365 mg of radicicol, 11-carbamoylundecanoyl chloride prepared from 900 mg of 11-carbamoylundecanoic acid, 8 ml of dry methylene chloride, 0.97 ml of pyridine and a catalytic amount of dimethylaminopyridine, 273 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-4c7b9d65f530406793bf5a3995ba53ef
Source dataset
uspto-grants-1997_07
Patent number
US05650430

Reaction notes

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