Bromine → HCID 22098222, compound

HRID 266208Notes

Reaction equation

HRID 266208 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([N:16]3[CH2:20][CH2:19][N:18]([CH2:21][CH2:22][C:23]([O:25][CH3:26])=[O:24])[C:17]3=[O:27])=[C:12]([S:28][CH3:29])[CH:11]=2)=[CH:6][CH:5]=1)(=[NH:3])[NH2:2].BrBr.C([O-])(=[O:34])C.[Na+]>C(O)(=O)C>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([C:10]2[CH:15]=[CH:14][C:13]([N:16]3[CH2:20][CH2:19][N:18]([CH2:21][CH2:22][C:23]([O:25][CH3:26])=[O:24])[C:17]3=[O:27])=[C:12]([S:28]([CH3:29])=[O:34])[CH:11]=2)=[CH:8][CH:9]=1)(=[NH:2])[NH2:3]

Participants

5

Reactant 3

HCID 24408BromineHCID 517045Sodium AcetateHCID 22098345HCID 22098345, compound

Product 1

HCID 22098222HCID 22098222, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Prepared from 1-(4'-amidino-3-methylthio-4-biphenylyl)-3-(2-methoxycarbonyl-ethyl)-imidazolidin-2-one by oxidation with bromine in glacial acetic acid in the presence of sodium acetate at ambient temperature.

Sources & evidence

ORD record
ord-b1c41bcca4d745cb9b407e0853425929
Source dataset
uspto-grants-1997_07
Patent number
US05650424

Reaction notes

Loading…