化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Cyanide → Ethyl o-cyanomethylcinnamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Cyanide | HCID 8929 | — |
| 反応物 | Ethyl 3-[2-(bromomethyl)phenyl]prop-2-enoate | HCID 54228366 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Ethyl o-cyanomethylcinnamate | HCID 53697120 | — |
反応手順
A solution of ethyl o-(bromomethyl)cinnamate (94.1 g., 0.35 mole), and sodium cyanide (20.6 g., 0.42 mole) in ethanol (450 ml.) is heated at reflux for 3 hours. About half of the ethanol is removed at reduced pressure. To the residue is added 500 ml. of water. The oily product is taken up in ether, washed with water, and dried over magnesium sulfate. Evaporation of the ether affords the title compound as an oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04150235 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-ef18fa6e636b4f14876fac19aacec3d6 |
| 出典メモ | uspto-grants-1979_04 |