HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 15392144, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Piperidine, 1-(2-chloroethyl)-, hydrochloride | HCID 74826 | — |
| Reactant | HCID 178515057 | HCID 178515057 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 15392144 | HCID 15392144 | 60.2% |
Reaction Steps
Following a procedure similar to that described above in Example 33A, 0.69 g (0.002 mol) of 2-(5-mercapto-1,3,4-thiadiazol-2-ylthiomethyl)saccharin was reacted with 0.74 g (0.004 mol) of 1-(2-chloroethyl)piperidine hydrochloride in 4 ml of DMF in the presence of 0.4 g of triethylamine to give 0.55 g (60%) of 2-(5-[2-(1-piperidinyl)ethylthio]-1,3,4-thiadiazol-2-ylthiomethyl)saccharin, mp 100.0°-101.0° C. (from ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05650422 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-e423b5c7d27845d2b86020810a16558d |
| Source note | uspto-grants-1997_07 |