HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 44341377, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | HCID 70047012 | HCID 70047012 | — |
| Reactant | HCID 178527989 | HCID 178527989 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 44341377 | HCID 44341377 | 76% |
Reaction Steps
By the method of Example 44 condensation of 2-chloromethyl-4-propyl-5,6-dimethoxysaccharin (0.6 g) and 1-phenyltetrazol-5-thiol sodium salt (0.36 g) in dimethylformamide (5 mL) and purification of the product by column chromatography on silica gel using ethyl acetate-hexane (3:7) as eluant followed by trituration with hexane afforded 2-(1-phenyltetrazol-5-yl)thiomethyl-4-propyl-5,6-dimethoxysaccharin, 0.65 g, 76% yield, mp 145°-146° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05650422 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-b43b1aba428b4f0891348c7eaa96ab4e |
| Source note | uspto-grants-1997_07 |