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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 26671Generated: October 27, 2026

Anisole → N-(4-formyl-3-hydroxyphenyl)acetamide

https://huagongshe.com/reaction/26671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnisoleHCID 7519—
Reactant3-HydroxyacetanilideHCID 12124—
ProductN-(4-formyl-3-hydroxyphenyl)acetamideHCID 12264699—

Reaction Steps

By operating according to Example 13, but using anisole as the solvent and a temperature of 100° C., and starting from 15.1 g of 3-acetylaminophenol, 9.0 g of a product (yield on the theoretical value=50%) having a melting point at 185°-186° C. were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04151201
Source datasetuspto-grants-1979_04
ORD IDord-21f595ce2255497e8b72055a7472fa8b
Source noteuspto-grants-1979_04