HCID 54310084, compound → Ethyl 2-(2,4-dimethoxyphenyl)propionate

HRID 26683Notes

Reaction equation

HRID 26683 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11](=[CH2:17])[C:12]([O:14][CH2:15][CH3:16])=[O:13]>C(O)C.[Pt]=O>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH:11]([CH3:17])[C:12]([O:14][CH2:15][CH3:16])=[O:13]

Participants

4

Reactant 1

HCID 54310084HCID 54310084, compound

Product 1

HCID 21322004Ethyl 2-(2,4-dimethoxyphenyl)propionate

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

Ethyl-2-(2,4-dimethoxyphenyl)propenoate (22.8 g--from step (b) above) was taken up in ethanol (300 ml) and hydrogenated at atmospheric pressure and room temperature with platinum oxide (0.6 g). The catalyst was removed by filtration (using `Hyflo` supercel), the ethanol evaporated in vacuo and the residue distilled affording the title compound: 12.64 g, bp 110°-5° C./0.25 mm

Workup

  1. customThe catalyst was removed by filtration (
  2. customevaporated in vacuo
  3. distillationthe residue distilled

Sources & evidence

ORD record
ord-7ebaa7683d8f465c8a588b0cc3b33e5f
Source dataset
uspto-grants-1979_04
Patent number
US04151179

Reaction notes

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