HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargyl bromide → 7-(2-Propyn-1-yloxy)-2H-1-benzopyran-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Umbelliferone | HCID 5281426 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 7-(2-Propyn-1-yloxy)-2H-1-benzopyran-2-one | HCID 3051101 | 60% |
Reaction Steps
In 100 ml DMF at 70° C. for 12 hours, 0.1 mole 7-hydroxy-coumarin is reacted with 0.1 mole propargyl bromide in the presence of 0.1 mole potassium carbonate. The compound of the title is obtained at a 60% yield. This compound melts at 118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151291 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-65bf7f0d4bdc4cc0983572099323cd68 |
| Source note | uspto-grants-1979_04 |