HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 4-Methylumbelliferone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Resorcinol | HCID 5054 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 4-Methylumbelliferone | HCID 5280567 | 77% |
Reaction Steps
0.1 mole resorcinol and 0.1 mole ethyl acetylacetate in solution in 100 ml concentrated sulphuric acid are maintained at 5° C. for 3 hours. After recyrstallisation of the solid formed from ethanol, there are obtained 12.5 grams 4-methyl-7-hydroxy-coumarin, melting at 185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151291 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-a79709e505384a2687bef6e5cd029a87 |
| Source note | uspto-grants-1979_04 |