HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-o-Nitrophenyl-7-hydroxy-coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Resorcinol | HCID 5054 | — |
| Reactant | Ethyl 2-nitro-beta-oxobenzenepropanoate | HCID 10561837 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-o-Nitrophenyl-7-hydroxy-coumarin | HCID 54474078 | 63.6% |
Reaction Steps
0.1 mole resorcinol is reacted with 0.1 mole ethyl o-nitrobenzoylacetate in methanol at 0° C. while passing through for one hour gaseous hydrochloric acid, and then maintaining at ambient temperature for 24 hours. After recrystallisation from an acetone-water mixture, there are obtained 18 grams 4-o-nitrophenyl-7-hydroxy-coumarin. This compound melts at 230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151291 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-1b7a2826ebc3451ba66fba2d3b5de144 |
| Source note | uspto-grants-1979_04 |