Ethyl bromoacetate → 1-Ethoxycarbonylmethyl-3-phenyl-benzimidazolium bromide

Participants

Reaction Steps

Using the procedure of Step B of Example 1, 1-phenylbenzimidazole [prepared from N-phenyl-o-phenylenediamine with 4HCl and formic acid] and ethyl bromoacetate were reacted to obtain a 56% of 1-ethoxycarbonylmethyl-3-phenyl-benzimidazolium bromide which after crystallization from a mixture of ethyl acetate and methanol melted at 180°-181° C.

Provenance & Evidence