反应详情

A solution of 20 g. of 4-hydroxybenzoic acid in 200 ml. of benzene and 40 ml. of acetyl chloride is refluxed for 3 hours. Solvent and excess acetyl chloride are evaporated. The mixture is dissolved in methanol (150 ml.) and water (20 ml.) added; after 15 minutes, addition of more water results in the precipitation of 4-acetoxy benzoic acid, m.p. 192°-193° C.

1. customSolvent and excess acetyl chloride are evaporated
2. dissolutionThe mixture is dissolved in methanol (150 ml.)
3. additionwater (20 ml.) added
4. additionaddition of more water