Potassium Hydroxide → HCID 21497372, compound

HRID 267278Notes

Reaction equation

HRID 267278 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][C:15]([F:18])=[CH:14][C:3]=1[C:4]([C:6]1[C:11]([F:12])=[CH:10][CH:9]=[CH:8][C:7]=1[F:13])=O.[OH-].[K+]>C(O)COCCO>[F:18][C:15]1[CH:14]=[C:3]([CH2:4][C:6]2[C:7]([F:13])=[CH:8][CH:9]=[CH:10][C:11]=2[F:12])[C:2](=[CH:17][CH:16]=1)[NH2:1]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 21497396HCID 21497396, compound

Product 1

HCID 21497372HCID 21497372, compound

Reagents, catalysts & solvents 1

HCID 8117Diethylene GlycolSolvent

Procedure

In the manner given in Preparation 11, 2-amino-2',5,6'-trifluorobenzophenone is refluxed with potassium hydroxide in diethylene glycol to give 4-fluoro-α-(2,6-difluorophenyl)-0-toluidene.

Workup

  1. customto give 4-fluoro-α-(2,6-difluorophenyl)-0-toluidene

Sources & evidence

ORD record
ord-e2dcb687648b4ec4ab90ff08bca6839b
Source dataset
uspto-grants-1976_03
Patent number
US03941802

Reaction notes

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