Ethyl orthoformate → 5-Methyl-1-[alpha-(o-chlorophenyl)-o-tolyl]imidazole

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Ethyl orthoformate	HCID 31214	—
Edukt	(2-Methyl-1,3-dioxolan-2-yl)methanamine	HCID 12434663	—
Edukt	2-[(2-Chlorophenyl)methyl]aniline	HCID 13426664	—
Katalysator	Titanium Tetrachloride	HCID 24193	—
Produkt	5-Methyl-1-[alpha-(o-chlorophenyl)-o-tolyl]imidazole	HCID 21497387	—

Reaktionsschritte

In the manner given in Example 3, α-(0-chlorophenyl)-0-toluidine is reacted with triethyl orthoformate, the resulting oil is heated with 2-methyl-2-(aminomethyl)-1,3-dioxolane, and the resulting product treated with titanium tetrachloride to give 5-methyl-1-[α-(0-chlorophenyl)-0-tolyl]imidazole.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US03941802
Quelldatensatz	uspto-grants-1976_03
ORD ID	ord-34e25510f4724abf9cc493908612ca66
Quellennotiz	uspto-grants-1976_03