1,4,4-Trimethyl-7-(3-methyloctan-2-yl)-1,2,3,4-tetrahydrobenzo[b]cyclopenta[d]pyran-9-ol → HCID 68135090, compound

HRID 267341Notes

Reaction equation

HRID 267341 reaction equation
[OH:1][C:2]1[C:7]2[C:8]3[CH:16]([CH3:17])[CH2:15][CH2:14][C:9]=3[C:10]([CH3:13])([CH3:12])[O:11][C:6]=2[CH:5]=[C:4]([CH:18]([CH:20]([CH3:26])[CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH3:19])[CH:3]=1.[ClH:27].[N:28]1([CH2:34][CH2:35][CH2:36][C:37](O)=[O:38])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[ClH:27].[CH3:26][CH:20]([CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH:18]([C:4]1[CH:3]=[C:2]([O:1][C:37](=[O:38])[CH2:36][CH2:35][CH2:34][N:28]2[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]2)[C:7]2[C:8]3[CH:16]([CH3:17])[CH2:15][CH2:14][C:9]=3[C:10]([CH3:13])([CH3:12])[O:11][C:6]=2[CH:5]=1)[CH3:19]

Participants

3

Reactant 2

HCID 30436311,4,4-Trimethyl-7-(3-methyloctan-2-yl)-1,2,3,4-tetrahydrobenzo[b]cyclopenta[d]pyran-9-olHCID 131720814-(Piperidin-1-yl)butanoic acid hydrochloride

Product 1

HCID 68135090HCID 68135090, compound

Procedure

9-hydroxy-7-(3-methyl-2-octyl)-1,4,4-trimethyl-1,2,3,4-tetrahydrocyclopenta[ c][1]benzopyran from Example 24 is reacted with γ-piperidinobutyric acid hydrochloride following the procedure of Example 2 to form 7-(3-methyl-2-octyl)-9[4-(piperidino)-butyryloxy]-1,4,4-trimethyl-1,2,3,4-tetrahydrocyclopenta[ c][1]benzopyran hydrochloride.

Sources & evidence

ORD record
ord-3b11b5e094054b86b686d45f3be3c6e2
Source dataset
uspto-grants-1976_03
Patent number
US03941782

Reaction notes

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