Dimethyl Sulfate → HCID 21556069, compound

HRID 267381Notes

Reaction equation

HRID 267381 reaction equation
[SH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([OH:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:10][CH:9]=1.[OH-].[Na+].S(OC)(O[CH3:27])(=O)=O>O>[CH3:27][S:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([OH:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:10][CH:9]=1

Participants

5

Reactant 3

HCID 6497Dimethyl SulfateHCID 14798Sodium HydroxideHCID 21556248HCID 21556248, compound

Product 1

HCID 21556069HCID 21556069, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
40 °C

Procedure

To 3.85 g. of ethyl 2'-mercapto-4-biphenylylglycolate is 40 ml. of water containing 0.65 g. of sodium hydroxide is added 2 ml. of dimethyl sulfate with stirring. The reaction mixture is gradually warmed to 40°C and stirred for 2 hours. The mixture is cooled and extracted with ether which is washed with water, dried and evaporated in vacuo. The residue is distilled to obtain ethyl 2'-methylthio-4-biphenylylglycolate.

Workup

  1. temperatureThe mixture is cooled
  2. extractionextracted with ether which
  3. washis washed with water
  4. customdried
  5. customevaporated in vacuo
  6. distillationThe residue is distilled

Sources & evidence

ORD record
ord-3a8ab779115344e887517b8941d5b5a2
Source dataset
uspto-grants-1976_03
Patent number
US03941821

Reaction notes

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