反应详情

To a solution of 300 ml. of anhydrous ethanol and 0.15 moles of sodium thiocyanate is added 35 g. (0.12 moles) of α, 2'-dichloro-4-biphenylylacetic acid and stirred for 15 hours. The reaction mixture is filtered and washed with absolute ethanol. The filtrate is evaporated to dryness, the residue is dissolved in 250 ml. of ether and washed several times with water. The ether is then dried and evaporated to dryness to obtain α-thiocyanato-2'-chloro-4-biphenylylacetic acid.

1. filtrationThe reaction mixture is filtered
2. washwashed with absolute ethanol
3. customThe filtrate is evaporated to dryness
4. dissolutionthe residue is dissolved in 250 ml
5. washof ether and washed several times with water
6. dry with materialThe ether is then dried
7. customevaporated to dryness