HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aminoacetaldehyde → 1-(alpha-Phenyl-o-tolyl)imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aminoacetaldehyde | HCID 363 | — |
| Reactant | Trimethyl orthoformate | HCID 9005 | — |
| Reactant | 2-Benzylaniline | HCID 119805 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 1-(alpha-Phenyl-o-tolyl)imidazole | HCID 21497358 | — |
Reaction Steps
In the manner given in Preparation 21, α-phenyl-o-toluidine is reacted first with trimethyl orthoformate, the resulting product is reacted with aminoacetaldehyde, dimethyl acetal, and the resulting product of this reaction is heated with titanium tetrachloride in monoglyme to give 1-(α-phenyl-o-tolyl)imidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03941803 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-95c6e07595134a3592a956073228a28d |
| Source note | uspto-grants-1976_03 |