5-Methyl-1-[alpha-(o-chlorophenyl)-o-tolyl]imidazole → 2'-Chloro-2-(5-methylimidazol-1-yl)benzophenone

HRID 267418Notes

Reaction equation

HRID 267418 reaction equation
[CH3:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[Cl:20])[CH:5]=[N:4][CH:3]=1.CC(C)=[O:23].OS(O)(=O)=O.O=[Cr](=O)=O>C(O)(=O)C>[Cl:20][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[C:13](=[O:23])[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[N:6]1[C:2]([CH3:1])=[CH:3][N:4]=[CH:5]1

Participants

4

Reactant 2

HCID 214973875-Methyl-1-[alpha-(o-chlorophenyl)-o-tolyl]imidazoleHCID 131709961Jones' reagent

Product 1

HCID 214973702'-Chloro-2-(5-methylimidazol-1-yl)benzophenone

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In the manner given in Preparation 44, 5-methyl-1-[α-(o-chlorophenyl)-o-tolyl]imidazole in acetic acid is heated with Jones reagent to give 2'-chloro-2-(5-methylimidazol-1-yl)benzophenone.

Sources & evidence

ORD record
ord-4a26c409b2144b2d95ebd87741f64ceb
Source dataset
uspto-grants-1976_03
Patent number
US03941803

Reaction notes

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