Formaldehyde → HCID 21555876, compound

HRID 267427Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:22])[C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[N:16]1[C:20]([CH3:21])=[CH:19][N:18]=[CH:17]1.[CH2:23]=[O:24]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:22])[C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[N:16]1[C:20]([CH3:21])=[CH:19][N:18]=[C:17]1[CH2:23][OH:24]

Participants

Reactant 2

HCID 712Formaldehyde

HCID 21497388HCID 21497388, compound

Product 1

HCID 21555876HCID 21555876, compound

Procedure

In the manner given in Example 1, 2',5 -dichloro-2-(5-methylimidazol-1-yl)benzophenone is heated in a bomb to 150° C. with 37% aqueous formaldehyde solution to give 2',5-dichloro-2-[2-(hydroxymethyl)-5-methylimidazol-1-yl]benzophenone.

Sources & evidence

ORD record: ord-e91620bd89e946f98f7108fccfdfa79e
Source dataset: uspto-grants-1976_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03941803

Reaction notes

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