Hydrazine → HCID 21555855, compound

HRID 267450Notes

Reaction equation

HRID 267450 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:18]2[CH:22]=[CH:21][N:20]=[C:19]2[CH2:23][N:24]2C(=O)C3=CC=CC=C3C2=O)=[C:6]([CH:17]=1)[C:7]([C:9]1[C:14]([F:15])=[CH:13][CH:12]=[CH:11][C:10]=1[F:16])=O.NN>C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:18]3[CH:22]=[CH:21][N:20]=[C:19]3[CH2:23][N:24]=[C:7]([C:9]3[C:10]([F:16])=[CH:11][CH:12]=[CH:13][C:14]=3[F:15])[C:6]=2[CH:17]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 21555837HCID 21555837, compound

Product 1

HCID 21555855HCID 21555855, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In the manner given in Example 33, 5-chloro-2',6'-difluoro-2-[2-(phthalimidomethyl)imidazol-1-yl]benzophenone in ethanol is heated with hydrazine to give 8-chloro-6-(2,6-difluorophenyl)-4H-imidazo[1,2-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-de16ad3c67524ecea1951a94ce31dc75
Source dataset
uspto-grants-1976_03
Patent number
US03941803

Reaction notes

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