Carbon Dioxide → N-[3-(Dimethylamino)-1,1-dimethylbutyl]-2-propenamide

Participants

Reaction Conditions

Reaction Steps

A mixture of 144.7 parts (0.63 mole) of N-(1,1-dimethyl-3-dimethylaminobutyl)-3-methoxypropionamide, 1 part of solid sodium hydroxide and 1 part of hydroquinone is charged to a reaction flask fitted with a condenser with a Dry Ice-cooled receiver, a stirrer and temperature control means. The pressure in the flask is reduced to less than 5 mm. and the flask is heated to 80° C. Vigorous reaction begins and liquid condenses in the receiver. After about one-half hour, the temperature is increased to 90° C. and this temperature is maintained for 3 hours. The product is distilled and the desired N-(1,1-dimethyl-3-dimethylaminobutyl)acrylamide is obtained at 80°-91° C./0.3-0.4 mm. The yield is 109.1 parts, or 87.4% of the theoretical amount, and the nitrogen percentage is the calculated 14.1%.

Provenance & Evidence