反应详情

To a solution of 0.05 mole of the product of Example 1 in 50 ml. of methyl alcohol, 30 ml. of 40% methanolic potassium hydroxide is added and the mixture is refluxed for 0.5 hours. The solvent is removed in vacuo, the residue dissolved in water, acidified and extracted with chloroform. The chloroform extract is washed with water, dried and concentrated to give the title compound as a thick oil.

1. temperaturethe mixture is refluxed for 0.5 hours
2. customThe solvent is removed in vacuo
3. dissolutionthe residue dissolved in water
4. extractionextracted with chloroform
5. extractionThe chloroform extract
6. washis washed with water
7. customdried
8. concentrationconcentrated