Potassium Hydroxide → chrysanthemic acid d-trans-form

Participants

Reaction Steps

In a 100 ml volume four-necked flask, there were charged methyl chrysanthemate consisting of 40.0 % of the cis-isomer and 60.0 % of the trans-isomer (20.0 g; trans-isomer, 0.066 mol), a 10 % aqueous solution of potassium hydroxide (33 g; 0.059 mol) and methanol (20 g), and the mixture was stirred at 50°C for 4 hours as in Example 1. After the removal of methanol by distillation, the reaction mixture was treated as in Example 4 to give trans-chrysanthemic acid (9.4 g; trans-isomer, 83 %) and unreacted methyl chrysanthemate (9.6 g).

Provenance & Evidence