Sulfuric Acid → HCID 53784359, compound

Participants

Reaction Steps

22.6 g (0.1 mol) of 3-(4-aminobenzenesulfonyl)acrylamide, prepared by hydrolysis of 3-(4-aminobenzenesulfonyl acrylonitrile with a 1:1 molar mixture of concentrated sulfuric acid and water, is dissolved in dimethylformamide (100 ml), and 14.5 ml triethylamine (0.1 mol) are added thereto. A solution of p-toluenesulfonyl chloride (19.1 g, 0.1 mol) in 50 ml dimethylformamide is added dropwise at room temperature, and the reaction mixture is left undisturbed for 16 hours. The product is recovered by precipitation with water and recrystallization from ethanol. There is thus produced 3-[4-(4-methylbenzenesulfonamido)benzenesulfonyl]acrylamide: ##SPC14##

Provenance & Evidence