Water → 3-[4-(4-Fluorobenzenesulfonamido)benzenesulfonyl]acrylonitrile

Participants

Reaction Steps

24 g (0.12 mol) of 3-(4-aminobenzenesulfonyl)acrylonitrile are dissolved in 200 ml acetone. 23.4 g (0.12 mol) of a solution of p-fluorobenzenesulfonyl chloride in 100 ml acetone are added thereto in several portions at room temperature, followed by 28 ml (0.12 mol) tributylamine. After standing for 8 hours at room temperature the reaction mixture is poured into 1 liter of water to separate the reaction product, which is then taken up in chloroform, and treated as described hereinabove to give 3-[4-(4-fluorobenzenesulfonamido)benzenesulfonyl]acrylonitrile: ##SPC21##

Provenance & Evidence