HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isocyanic acid → 2,5-Dimethyl-3,6-dihexyl-pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isocyanic acid | HCID 6347 | — |
| Reactant | 2-Nonanone | HCID 13187 | — |
| Reactant | Nitrosyl chloride | HCID 17601 | — |
| Reactant | 3-Oximino-2-nonanone | HCID 73682634 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2,5-Dimethyl-3,6-dihexyl-pyrazine | HCID 21814939 | — |
Reaction Steps
h. 2,5-Dimethyl-3,6-dihexyl-pyrazine was prepared by first forming 3-oximino-2-nonanone by reacting 2-nonanone with nitrosyl chloride according to the method of BOUVEAULT (loc.cit.). The autocondensation of two moles of the imino-ketone in the presence of zinc and acetic acid [according to the method described in Chimia 11, 310 (1957)] yielded 2,5-dimethyl-3,6-dihexyl-pyrazine which had a b.p. of 112°-120°C./0.01 mm. Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03943260 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-aac9aaea7a43424d8d4d18380ddd96d4 |
| Source note | uspto-grants-1976_03 |