Ethyl chloroformate → HCID 21553699, compound

Participants

Reaction Steps

1-Trichloromethyl-3-(3',4'-dichlorophenyl)-3-hydroxyurea (16.9 grams; 0.05 mol) is dissolved in dioxane (75 ml) and mixed with 2N aqueous sodium hydroxide (30 ml). Ethyl chloroformate (5.7 ml; 0.06 mol) is then added dropwise to the mixture with stirring, resulting in the formation of a precipitate. The precipitate is recovered by filtration, washed with water and dried to yield 2-(3', 4'-dichlorophenyl)-4-trichloromethyl-1,2,4-oxadiazolidine-3,5-dione.

Provenance & Evidence