Sodium Methoxide → HCID 68141029, compound

Participants

Reaction Steps

3.2 gms (.01 mole) of 2-amino-1-n-butyl-4-n-butylamino-6-chloro-5-cyano-pyridinium chloride (compound 6 - Table 1) was dissolved in dry dimethylformamide, 0.06 gms (0.01 mole) of sodium methoxide added, and the mixture refluxed for 60 minutes, filtered and solvent evaporated off. The solid was recrystallised from acetone to give 1.0 gm (30% yield) of 2-amino-1-n-butyl-4-n-butylamino-5-cyano-6-methoxy pyridinium chloride (MPt 187° - 189°C.)

Provenance & Evidence