Thionyl Chloride → HCID 54412737, compound

Participants

Reaction Steps

A solution of 17 g of α-[para-(1-cyclohexenyl)-phenyl]-propionic acid in 100 ml of absolute benzene is treated with 8 ml of thionyl chloride and then heated at 80°-90°C for one hour. The solution is evaporated under reduced pressure, the residue dissolved in 3 × 50 ml of absolute benzene, followed each time by evaporation under reduced pressure. There is thus obtained as residue α-[para-(1-cyclohexenyl)-phenyl]-propionic acid chloride which can be used as it is for the manufacture of the afore-described ester.

Provenance & Evidence