HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-(3-fluorophenyl)adamantane-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-Fluoroaniline | HCID 9742 | — |
| Reactant | 1-Adamantanecarbonyl chloride | HCID 98915 | — |
| Solvent | Chloroform hexane | HCID 21585165 | — |
| Product | N-(3-fluorophenyl)adamantane-1-carboxamide | HCID 2839369 | — |
Reaction Steps
Subject 3.6 g. (18 mmoles) of adamantane carboxylic acid chloride, 2.0 g. of m-fluoroaniline and 8.0 ml. of triethylamine to the process of Example 11. Crystallize the residue obtained thereby from a mixture of chloroform-hexane to obtain the title product, m.p. 174°-177°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03944675 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-14dd8eb3536a47e2a28ac091ce23d6f2 |
| Source note | uspto-grants-1976_03 |