Nicotinic Acid → HCID 86733169, compound

Participants

Reaction Conditions

Reaction Steps

Hexetidine (1 mole) was dissolved in 1,000 ml methanol and heated to 50°C. To the solution nicotinic acid (1 mole) was added dropwise. After stirring for 1.5 hours at 50°C, half of the solvent was distilled off under vacuum at 40°C. The crystal slurry obtained at room temperature was filtered and recrystallized from acetic acid ethyl ester, yielding hexetidine nicotinate as white crystals.

Provenance & Evidence