Nicotinic Acid → HCID 86733169, compound

HRID 267911Notes

Reaction equation

HRID 267911 reaction equation
[CH3:1][CH2:2][CH2:3][CH2:4][CH:5]([CH2:8][N:9]1[CH2:14][N:13]([CH2:15][CH:16]([CH2:19][CH2:20][CH2:21][CH3:22])[CH2:17][CH3:18])[CH2:12][C:11]([NH2:24])([CH3:23])[CH2:10]1)[CH2:6][CH3:7].[C:25]([OH:33])(=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[N:28][CH:27]=1>C1C=CC=CC=1>[CH3:22][CH2:21][CH2:20][CH2:19][CH:16]([CH2:15][N:13]1[CH2:14][N:9]([CH2:8][CH:5]([CH2:4][CH2:3][CH2:2][CH3:1])[CH2:6][CH3:7])[CH2:10][C:11]([NH2:24])([CH3:23])[CH2:12]1)[CH2:17][CH3:18].[C:25]([O-:33])(=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[N:28][CH:27]=1

Participants

4

Reactant 2

HCID 938Nicotinic AcidHCID 3607Hexetidine

Product 1

HCID 86733169HCID 86733169, compoundYield 60%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Hexetidine (0.1 mole) was dissolved in benzene at 40°C and nicotinic acid was added dropwise. The solution was reacted for 2 hours and cooled under stirring to yield crystals of hexetidine nicotinate which were filtered and dried.

Workup

  1. customThe solution was reacted for 2 hours
  2. temperaturecooled

Sources & evidence

ORD record
ord-9a7f124a8c524896aab52c8df30428cc
Source dataset
uspto-grants-1976_03
Patent number
US03946013

Reaction notes

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