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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 267947Generated: October 25, 2026

Methanol → 2-Amino-5-bromo-3-methoxypyrazine

https://huagongshe.com/reaction/267947

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant2-Amino-3,5-dibromopyrazineHCID 620004—
ReactantSodiumHCID 5360545—
Product2-Amino-5-bromo-3-methoxypyrazineHCID 11344724—

Reaction Steps

2-Amino-3,5-dibromopyrazine (7 g.) is boiled for about 9 hours with 0.65 g. sodium in 18.5 ml. methanol to give 2-amino-3-methoxy-5-bromopyrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03946009
Source datasetuspto-grants-1976_03
ORD IDord-3e15daad8f7a4aa58c4f198afd004c7e
Source noteuspto-grants-1976_03