HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 7H-indolizino[5,6,7-ij]isoquinolin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 7-hydroxyimino-7H-indolizino[5,6,7-ij]isoquinoline | HCID 136353514 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 7H-indolizino[5,6,7-ij]isoquinolin-7-one | HCID 21552875 | — |
Reaction Steps
The 7-Imino-7H-indolizino[5,6,7-ij]isoquinoline (110 g.) and N sodium hydroxide solution ( ##SPC14## cc.) in ethanol (4.4 liters) and water (4.4 liters) are heated under reflux for 4 hours. After cooling, 7H-indolizino[5,6,7-ij]isoquinolin-7-one (108.1 g.) is obtained in the form of yellow needles melting at 264° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03946019 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-af67098dedfa47c39e05fd40943f9d1d |
| Source note | uspto-grants-1976_03 |